Features include

  • Microsoft Windows commands and user interface
  • rapid import of source data as a simple text(ASCII)file containing all original observations
  • display of the distribution with a possibility to rapidly calculate any percentile and the corresponding confidence limits
  • estimation of non-parametric reference limits, median or any percentile in the distribution with the corresponding confidence limits
  • possibility to choose statistically optimized bin width for illustrative presentation of frequency histograms
  • display of two distributions for comparison of health- and illness-related data
  • automatic updating of clinical sensitivity and specificity values with mouse movement
  • display of clinical sensitivity and specificity with the corresponding confidence intervals, positive and negative likelihood ratios, predictive values and efficiency at any level of test result
  • rapid updating of predictive values and efficiency to any entered prior probability of disease
  • optional presentation of sensitivity, specificity and/or efficiency curves for the complete range of possible cutoff limits
  • Receiver operating characteristics (ROC-) curve features include
    • display of one or several curves
    • calculation of areas under curve by non-parametric method including estimation of respective standard errors for the area
    • statistical comparison of areas under two ROC curves either by the paired or unpaired method
    • statistical comparison of points on two ROC curves either by the paired or unpaired method
    • optional possibility to estimate partial areas under ROC curves
  • quick and simple data import and export between GraphROC and other software
  • easy export of graphs for editing and e.g. for making slides or figures for publication
  • The following features of the program have, to our knowledge, not been included in previously available laboratory test evaluation software:
  • possibility to automatically optimize the bin width for display of frequency histograms and producing non-parametric ROC curves (Kairisto, 1995)
  • possibility to estimate also partial areas under the ROC curve (see Zweig & Campbell, 1993)
  • estimation of non-parametric reference change limits and corresponding confidence limits
  • optional indirect estimation of "health" related limits from patient data, where majority of the values can be considered to be representative of health-related values
  • optional indirect estimation of "health" related change intervals from unselected or partially selected serial patient data, where majority of the values can be considered to be representative of health-related values (Kairisto, Virtanen, Uusipaikka et al. 1993)
  • Full advantage of all features in GraphROC for Windows will be achieved if the program is used together with other programs running under Microsoft Windows. Data import and export, graph export, and switching from one program to another allow convenient use of GraphROC together with other Windows applications.


GraphROC

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